Abstract
The major limitations of autogenous grafting are inadequate supply and surgical morbidity, including donor site pain, paresthesia, and infection. Graft resorption can also pose a severe problem. Bone induction is therefore needed to assist in fracture healing and to fill osseous defects. This article reviewed the current development of bone induction in relation to clinical orthodontics.
MeSH terms
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Alveolar Bone Loss / surgery
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Animals
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Bone Demineralization Technique
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Bone Marrow Transplantation
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Bone Matrix / transplantation
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Bone Morphogenetic Proteins / pharmacology
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Bone Transplantation / methods
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Chondrocytes / transplantation
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Drug Delivery Systems
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Fracture Healing / drug effects*
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Fracture Healing / physiology*
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Humans
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Mesoderm / cytology
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Orthognathic Surgical Procedures
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Osteoblasts / transplantation
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Osteogenesis / drug effects*
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Osteogenesis / physiology*
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Recombinant Proteins / pharmacology
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Stem Cell Transplantation
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Stress, Mechanical
Substances
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Bone Morphogenetic Proteins
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Recombinant Proteins