The prosthodontic aspects of a new method of reconstruction after maxillectomy are described. A custom-made titanium mesh tray filled with crushed autogenous hip bone is interposed between two layers of a pedicled temporal muscle flap. The titanium mesh tray is fabricated on a cast carved to represent the anatomy of the reconstructed maxilla. The tray is designed so that, after healing, osseointegrated implants can be placed in preplanned positions in the reformed maxilla. The buccal sulcus is recreated with a free mucosal graft from the contralateral cheek at the second implant surgical stage. The prosthodontic restoration is completed after healing of the free mucosal graft.