Abstract
We compared the clinical and laboratory features of human immunodeficiency virus (HIV)- and non-HIV-infected patients with penicilliosis marneffei. HIV-infected patients had a higher incidence of fungemia. A total of 85.7% of the HIV-negative patients had underlying diseases including hematologic malignancies or had received therapy with corticosteroids or cytotoxic agents. By a Penicillium marneffei-specific mannoprotein Mp1p enzyme-linked immunosorbent assay, serum antigen titers were found to be higher in HIV-positive patients, whereas serum antibody levels were found to be higher in HIV-negative patients.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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AIDS-Related Opportunistic Infections / diagnosis*
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AIDS-Related Opportunistic Infections / microbiology
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AIDS-Related Opportunistic Infections / physiopathology*
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Adolescent
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Adult
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Aged
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Antibodies, Fungal / blood
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Antigens, Fungal / analysis
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Child
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Culture Media
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Enzyme-Linked Immunosorbent Assay
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Female
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Fungemia / diagnosis
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Fungemia / microbiology
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Fungemia / physiopathology
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Humans
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Male
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Middle Aged
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Mycoses / diagnosis*
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Mycoses / microbiology
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Mycoses / physiopathology*
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Penicillium / growth & development
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Penicillium / isolation & purification*
Substances
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Antibodies, Fungal
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Antigens, Fungal
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Culture Media