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An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin.
Cell. 2001 Jun 29;105(7):891-902. doi: 10.1016/s0092-8674(01)00407-x.
Cell. 2001.
PMID: 11439185
Free article.
Parkin is a component of an SCF-like ubiquitin ligase complex and protects postmitotic neurons from kainate excitotoxicity.
Staropoli JF, McDermott C, Martinat C, Schulman B, Demireva E, Abeliovich A.
Staropoli JF, et al.
Neuron. 2003 Mar 6;37(5):735-49. doi: 10.1016/s0896-6273(03)00084-9.
Neuron. 2003.
PMID: 12628165
Free article.
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