Abstract
This study evaluated the applicability of quantitative PCR (Q-PCR) and branched-chain DNA assays for detection of hepatitis B virus (HBV) DNA in sera. For 42 samples, the detection rates were 81 and 41%, respectively, with a correlation coefficient of 0.633. The Q-PCR is useful for early monitoring of HBV load in high-risk patients.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Aged
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Carcinoma, Hepatocellular / blood
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Carcinoma, Hepatocellular / virology*
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DNA Primers
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DNA, Viral / blood*
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DNA, Viral / chemistry
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Female
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Hepatitis B Antibodies / blood
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Hepatitis B Core Antigens / blood
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Hepatitis B Surface Antigens / blood
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Hepatitis B virus / isolation & purification*
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Humans
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Liver Neoplasms / blood
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Liver Neoplasms / virology*
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Liver Transplantation*
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Male
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Middle Aged
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Polymerase Chain Reaction / methods
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Reproducibility of Results
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Sensitivity and Specificity
Substances
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DNA Primers
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DNA, Viral
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Hepatitis B Antibodies
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Hepatitis B Core Antigens
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Hepatitis B Surface Antigens