Mortality of sea lions along the central California coast linked to a toxic diatom bloom

Nature. 2000 Jan 6;403(6765):80-4. doi: 10.1038/47481.

Abstract

Over 400 California sea lions (Zalophus californianus) died and many others displayed signs of neurological dysfunction along the central California coast during May and June 1998. A bloom of Pseudo-nitzschia australis (diatom) was observed in the Monterey Bay region during the same period. This bloom was associated with production of domoic acid (DA), a neurotoxin that was also detected in planktivorous fish, including the northern anchovy (Engraulis mordax), and in sea lion body fluids. These and other concurrent observations demonstrate the trophic transfer of DA resulting in marine mammal mortality. In contrast to fish, blue mussels (Mytilus edulus) collected during the DA outbreak contained no DA or only trace amounts. Such findings reveal that monitoring of mussel toxicity alone does not necessarily provide adequate warning of DA entering the food web at levels sufficient to harm marine wildlife and perhaps humans.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Animals
  • Bivalvia / microbiology
  • Brain Diseases / chemically induced
  • Brain Diseases / veterinary
  • California
  • Chromatography, Liquid
  • Diatoms*
  • Eutrophication*
  • Fishes / microbiology
  • Food Chain
  • Humans
  • Kainic Acid / analogs & derivatives
  • Kainic Acid / analysis
  • Kainic Acid / poisoning
  • Marine Toxins / analysis
  • Marine Toxins / poisoning
  • Mass Spectrometry
  • Mortality
  • Neurotoxins / analysis
  • Neurotoxins / poisoning
  • Poisoning / veterinary
  • Sea Lions* / microbiology

Substances

  • Marine Toxins
  • Neurotoxins
  • domoic acid
  • Kainic Acid