Abstract
Bone marrow necrosis (BMN) is a rare pathologic entity associated with a wide variety of diseases. We describe a patient with chronic myeloid leukemia on interferon treatment, who developed BMN with symptoms and signs masquerading as interferon toxicity. This is followed by a literature review of BMN in CML.
MeSH terms
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Adult
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Antineoplastic Agents / therapeutic use
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Bone Marrow / pathology*
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Diagnosis, Differential
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Humans
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Hydroxyurea / therapeutic use
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Interferon alpha-2
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Interferon-alpha / adverse effects
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Interferon-alpha / therapeutic use*
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Leukemia, Myelogenous, Chronic, BCR-ABL Positive / pathology*
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Leukemia, Myelogenous, Chronic, BCR-ABL Positive / therapy*
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Male
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Necrosis
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Recombinant Proteins
Substances
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Antineoplastic Agents
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Interferon alpha-2
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Interferon-alpha
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Recombinant Proteins
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Hydroxyurea