Trisomy 8 as a secondary genetic change in acute megakaryoblastic leukemia associated with Down's syndrome

Leukemia. 1999 Mar;13(3):491-2. doi: 10.1038/sj.leu.2401330.
No abstract available

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Chromosomes, Human, Pair 8*
  • Down Syndrome / complications
  • Down Syndrome / genetics*
  • Female
  • Humans
  • In Situ Hybridization, Fluorescence
  • Infant
  • Karyotyping
  • Leukemia, Megakaryoblastic, Acute / complications
  • Leukemia, Megakaryoblastic, Acute / drug therapy
  • Leukemia, Megakaryoblastic, Acute / genetics*
  • Mitoxantrone / therapeutic use
  • Trisomy*

Substances

  • Mitoxantrone