Acinetobacter bacteremia in Hong Kong: prospective study and review

Clin Infect Dis. 1999 Jan;28(1):26-30. doi: 10.1086/515068.

Abstract

The epidemiological characteristics of 18 patients with acinetobacter bacteremia were analyzed. Patients (mean age, 55.5 years) developed bacteremia after an average of 14.1 days of hospitalization. Fifteen of 16 patients survived bacteremia caused by Acinetobacter baumannii. Cultures of blood from the remaining two patients yielded Acinetobacter lwoffii. Most patients (78%) resided in the general ward, while four patients (22%) were under intensive care. Genotyping by arbitrarily primed polymerase chain reaction analysis and the temporal sequence of isolation were more useful than phenotyping by antimicrobial susceptibility in the determination of the source of bacteremia, and the intravascular catheter was the leading infection source (39% of cases). The possibility of an association of glucose with the pathogenesis of acinetobacter infection was raised.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acinetobacter / classification
  • Acinetobacter / drug effects
  • Acinetobacter / isolation & purification*
  • Acinetobacter Infections / epidemiology*
  • Acinetobacter Infections / microbiology
  • Adult
  • Aged
  • Aged, 80 and over
  • Anti-Bacterial Agents / pharmacology
  • Bacteremia / epidemiology*
  • Bacteremia / microbiology
  • Bacterial Typing Techniques
  • Catheters, Indwelling / microbiology
  • DNA, Bacterial / analysis
  • Female
  • Hong Kong / epidemiology
  • Hospitalization
  • Humans
  • Male
  • Microbial Sensitivity Tests
  • Middle Aged
  • Polymerase Chain Reaction / methods
  • Prospective Studies

Substances

  • Anti-Bacterial Agents
  • DNA, Bacterial