Protein Family Models for Protein (Select 515501116) - Protein Family Models

Warning: The NCBI web site requires JavaScript to function. more...

Links from Protein

Items: 7

Select item 3917801.

Members of this family include both regulatory proteins such as Spx or MgsR and the arsenate reductase ArsC. Some ArsC proteins are selenoproteins.

Date:: 2023-12-12

Family Accession:: NF015893.4
Method:: HMM

Select item 3499682.

new record, indexing in progress

Family Accession:

Select item 3183993.

new record, indexing in progress

Family Accession:

Select item 1835754.

arsenate reductase family protein

arsenate reductase (ArsC) family protein similar to Synechocystis sp. arsenate reductases ArsI1 and ArsI2, which are glutaredoxin-dependent enzymes that catalyze the reduction of arsenate [As(V)] to arsenite [As(III)]

Date:: 2023-02-22

Family Accession:: 10122547
Method:: Sparcle

Select item 1802085.

new record, indexing in progress

Family Accession:

Select item 1800016.

new record, indexing in progress

Family Accession:

Select item 166707.

arsenate reductase (glutaredoxin)

This HMM describes a distinct clade, including ArsC itself, of the broader ArsC family described by Pfam PF03960. This clade is almost completely restricted to the Proteobacteria. An anion-translocating ATPase has been identified as the product of the arsenical resistance operon of resistance plasmid R773. When expressed in Escherichia coli this ATP-driven oxyanion pump catalyses extrusion of the oxyanions arsenite, antimonite and arsenate. The pump is composed of two polypeptides, the products of the arsA and arsB genes. The pump alone produces resistance to arsenite and antimonite. This protein, ArsC, catalyzes the reduction of arsenate to arsenite, and thus extends resistance to include arsenate. Some ArsC proteins are selenoproteins.