Protein Family Models for Protein (Select 496457981) - Protein Family Models

Select item 4008671.

Members of this family share a hexapeptide repeat-containing domain with acetyltransferases and succinyltransferases such as DapH, DapD, and GlmU.

Date:: 2023-12-12

Family Accession:: NF025953.4
Method:: HMM

Select item 3955662.

Tetrahydrodipicolinate succinyltransferase N-terminal

This domain is found at the N-terminus of tetrahydrodipicolinate N-succinyltransferase (DapH) which catalyses the acylation of L-2-amino-6-oxopimelate to 2-N-succinyl-6-oxopimelate in the meso-diaminopimelate/lysine biosynthetic pathway of bacteria, blue-green algae, and plants [1]. The N-terminal domain as defined here contains three alpha-helices and two twisted hairpin loops [2]. [1]. 11910040. Acyl group specificity at the active site of. tetrahydridipicolinate N-succinyltransferase.. Beaman TW, Vogel KW, Drueckhammer DG, Blanchard JS, Roderick SL;. Protein Sci 2002;11:974-979.. [2]. 9012664. Three-dimensional structure of tetrahydrodipicolinate. N-succinyltransferase.. Beaman TW, Binder DA, Blanchard JS, Roderick SL;. Biochemistry 1997;36:489-494. (from Pfam)

GO Terms:

Molecular Function:: tetrahydrodipicolinate N-acetyltransferase activity (GO:0047200)

Date:: 2024-04-03

Family Accession:: NF020092.4
Method:: HMM

Select item 3883783.

transferase-like hexapeptide repeat-containing protein

Date:: 2023-12-12

Family Accession:: NF012360.4
Method:: HMM

Select item 3594054.

new record, indexing in progress

Family Accession:

Select item 3545435.

new record, indexing in progress

Family Accession:

Select item 3465246.

new record, indexing in progress

Family Accession:

Select item 3313867.

new record, indexing in progress

Family Accession:

Select item 3285218.

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Family Accession:

Select item 3155719.

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Family Accession:

Select item 16892410.

new record, indexing in progress

Family Accession:

Select item 16861211.

new record, indexing in progress

Family Accession:

Select item 16389112.

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Family Accession:

Select item 16357913.

new record, indexing in progress

Family Accession:

Select item 14781514.

2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase

This enzyme is part of the diaminopimelate pathway of lysine biosynthesis. Alternate name: tetrahydrodipicolinate N-acetyltransferase. Note that IUBMB lists this alternate name as the accepted name. Unfortunately, the related succinyl transferase acting on the same substrate (EC:2.3.1.117, TIGR00695) uses the opposite standard. We have decided to give these two enzymes names which more clearly indicated that they act on the same substrate.

Gene:: dapD

GO Terms:

Biological Process:: lysine biosynthetic process via diaminopimelate (GO:0009089)

Molecular Function:: tetrahydrodipicolinate N-acetyltransferase activity (GO:0047200)

Date:: 2024-02-27

Family Accession:: TIGR03532.1
Method:: HMM

Select item 3954015.

new record, indexing in progress

Family Accession:

Select item 3863416.

new record, indexing in progress

Family Accession:

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