Protein Family Models for Protein (Select 493786768) - Protein Family Models

Select item 4078051.

This domain is found at the N-terminus of aminopeptidases from the M1 family. (from Pfam)

Date:: 2023-12-12

Family Accession:: NF037667.4
Method:: HMM

Select item 4010082.

ERAP1-like C-terminal domain-containing protein

This large domain is composed of 16 alpha helices organized as 8 HEAT-like repeats. This domain forms a concave face that faces towards the active site of the peptidase. [1]. 21478864. Structural basis for antigenic peptide precursor processing by. the endoplasmic reticulum aminopeptidase ERAP1.. Nguyen TT, Chang SC, Evnouchidou I, York IA, Zikos C, Rock KL,. Goldberg AL, Stratikos E, Stern LJ;. Nat Struct Mol Biol. 2011;18:604-613. (from Pfam)

Date:: 2024-04-03

Family Accession:: NF023266.4
Method:: HMM

Select item 3899193.

M1 family aminopeptidase

The M1 family metalloproteases in this family are zinc-dependent enzymes with aminopeptidase activity.

GO Terms:

Molecular Function:: metallopeptidase activity (GO:0008237)

Molecular Function:: zinc ion binding (GO:0008270)

Date:: 2024-04-03

Family Accession:: NF013592.4
Method:: HMM

Select item 3603004.

new record, indexing in progress

Family Accession:

Select item 3562175.

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Family Accession:

Select item 3483696.

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Family Accession:

Select item 3277967.

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Family Accession:

Select item 3260398.

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Family Accession:

Select item 3170159.

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Family Accession:

Select item 14614110.

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Family Accession:

Select item 14583711.

new record, indexing in progress

Family Accession:

Select item 3298912.

M1 family metallopeptidase

M1 family metallopeptidase containing an ERAP1-like C-terminal domain with HEAT-like repeats; similar to aminopeptidase N, a broad specificity aminopeptidase, and glutamyl aminopeptidase, which releases N-terminal glutamate from a peptide

GO Terms:

Molecular Function:: aminopeptidase activity (GO:0004177)

Biological Process:: proteolysis (GO:0006508)

Molecular Function:: zinc ion binding (GO:0008270)

Molecular Function:: metallopeptidase activity (GO:0008237)

Date:: 2022-10-25

Family Accession:: 10176184
Method:: Sparcle

Select item 2119013.

new record, indexing in progress

Family Accession:

Select item 817514.

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Family Accession:

Select item 776815.

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Family Accession:

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