RecName: Full=DNA damage-binding protein 1; AltName: Full=DDB p127 sub - Protein

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A DNA repair disorder caused by de novo monoallelic DDB1 variants is associated with a neurodevelopmental syndrome. [Am J Hum Genet. 2021]
A DNA repair disorder caused by de novo monoallelic DDB1 variants is associated with a neurodevelopmental syndrome.
White SM, Bhoj E, Nellåker C, Lachmeijer AMA, Marshall AE, Boycott KM, Li D, Smith W, Hartley T, McBride A, et al. Am J Hum Genet. 2021 Apr 1; 108(4):749-756. Epub 2021 Mar 19.
Knockdown of damage-specific DNA binding protein 1 (DDB1) enhances the HBx-siRNA-mediated inhibition of HBV replication. [Biologicals. 2008]
Knockdown of damage-specific DNA binding protein 1 (DDB1) enhances the HBx-siRNA-mediated inhibition of HBV replication.
Tang KF, Xie J, Chen M, Liu Q, Zhou XY, Zeng W, Huang AL, Zuo GQ, Wang Y, Xiang R, et al. Biologicals. 2008 May; 36(3):177-83. Epub 2008 Mar 4.
Structure of DDB1 in complex with a paramyxovirus V protein: viral hijack of a propeller cluster in ubiquitin ligase. [Cell. 2006]
Structure of DDB1 in complex with a paramyxovirus V protein: viral hijack of a propeller cluster in ubiquitin ligase.
Li T, Chen X, Garbutt KC, Zhou P, Zheng N. Cell. 2006 Jan 13; 124(1):105-17.

RefSeq genomic sequence
See the genomic reference sequence for the DDB1 gene (NG_032697.2).
RefSeq protein
See the reference protein sequence for DNA damage-binding protein 1 (NP_001914.3).

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Q16531 [Domain Mapping of Disease Mut...]
Q16531
Domain Mapping of Disease Mutations
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome
Evolutionary Trace of Functional Site [Evolutionary Trace of Functio...]
Evolutionary Trace of Functional Site

RecName: Full=DNA damage-binding protein 1; AltName: Full=DDB p127 subunit; AltN...
RecName: Full=DNA damage-binding protein 1; AltName: Full=DDB p127 subunit; AltName: Full=DNA damage-binding protein a; Short=DDBa; AltName: Full=Damage-specific DNA-binding protein 1; AltName: Full=HBV X-associated protein 1; Short=XAP-1; AltName: Full=UV-damaged DNA-binding factor; AltName: Full=UV-damaged DNA-binding protein 1; Short=UV-DDB 1; AltName: Full=XPE-binding factor; Short=XPE-BF; AltName: Full=Xeroderma pigmentosum group E-complementing protein; Short=XPCe
gi|12643730|sp|Q16531.1|DDB1_HUMAN

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