RecName: Full=Serine palmitoyltransferase 2; AltName: Full=Long chain - Protein

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Hepatic deletion of serine palmitoyl transferase 2 impairs ceramide/sphingomyelin balance, bile acids homeostasis and leads to liver damage in mice. [Biochim Biophys Acta Mol Cell ...]
Hepatic deletion of serine palmitoyl transferase 2 impairs ceramide/sphingomyelin balance, bile acids homeostasis and leads to liver damage in mice.
Lallement J, Raho I, Merlen G, Rainteau D, Croyal M, Schiffano M, Kassis N, Doignon I, Soty M, Lachkar F, et al. Biochim Biophys Acta Mol Cell Biol Lipids. 2023 Aug; 1868(8):159333. Epub 2023 May 22.
Upregulation of the serine palmitoyltransferase subunit SPTLC2 by endoplasmic reticulum stress inhibits the hepatic insulin response. [Exp Mol Med. 2022]
Upregulation of the serine palmitoyltransferase subunit SPTLC2 by endoplasmic reticulum stress inhibits the hepatic insulin response.
Kim GT, Devi S, Sharma A, Cho KH, Kim SJ, Kim BR, Kwon SH, Park TS. Exp Mol Med. 2022 May; 54(5):573-584. Epub 2022 May 5.
Impaired sphingolipid synthesis in the respiratory tract induces airway hyperreactivity. [Sci Transl Med. 2013]
Impaired sphingolipid synthesis in the respiratory tract induces airway hyperreactivity.
Worgall TS, Veerappan A, Sung B, Kim BI, Weiner E, Bholah R, Silver RB, Jiang XC, Worgall S. Sci Transl Med. 2013 May 22; 5(186):186ra67.

RefSeq protein
See the reference protein sequence for serine palmitoyltransferase 2 (NP_035609.1).

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MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF) [MODBASE, Database of Comparat...]
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF)
Mouse Genome Informatics (MGI) [Mouse Genome Informatics (MGI)]
Mouse Genome Informatics (MGI)
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome

TRIM16[gene] (60)
ClinVar
tripartite motif-containing protein 16 isoform c [Homo sapiens]
tripartite motif-containing protein 16 isoform c [Homo sapiens]
gi|1130413365|ref|NP_001335053.1|

Protein
Brx-11_CL#15
Brx-11_CL#15

biosample

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Protein