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Select item 112283411.

Mechanical loading and orthobiologic therapies in the treatment of post-traumatic osteoarthritis (PTOA): a comprehensive review

Mahammad Gardashli, Max Baron, Charles Huang, Lee D. Kaplan, Zhipeng Meng, Dimitrios Kouroupis, Thomas M. Best

Front Bioeng Biotechnol. 2024; 12: 1401207. Published online 2024 Jun 24. doi: 10.3389/fbioe.2024.1401207

PMCID:: PMC11228341

Abstract Article PDF–1.5M

Select item 108505772.

Protecting the regenerative environment: selecting the optimal delivery vehicle for cartilage repair—a narrative review

T. Mark Campbell, Guy Trudel

Front Bioeng Biotechnol. 2024; 12: 1283752. Published online 2024 Jan 25. doi: 10.3389/fbioe.2024.1283752

PMCID:: PMC10850577

Abstract Article PDF–1.1M

Select item 108056273.

JD-312 – A novel small molecule that facilitates cartilage repair and alleviates osteoarthritis progression

Jingduo Gao, Haixiang Pei, Fang Lv, Xin Niu, Yu You, Liang He, Shijia Hu, Karan M. Shah, Mingyao Liu, Yihua Chen, Bing Du, Hai Xiong, Jian Luo

J Orthop Translat. 2024 Jan; 44: 60–71. Published online 2023 Dec 30. doi: 10.1016/j.jot.2023.11.007

PMCID:: PMC10805627

Abstract Article PDF–6.4M

Select item 103766764.

Adipose-Derived Mesenchymal Stromal Cells: A Tool for Bone and Cartilage Repair

Ivana Roberta Romano, Floriana D’Angeli, Nunzio Vicario, Cristina Russo, Carlo Genovese, Debora Lo Furno, Giuliana Mannino, Serena Tamburino, Rosalba Parenti, Rosario Giuffrida

Biomedicines. 2023 Jul; 11(7): 1781. Published online 2023 Jun 21. doi: 10.3390/biomedicines11071781

PMCID:: PMC10376676

Abstract Article PDF–684K

Select item 103751055.

Cell‐Based Therapies for Degenerative Musculoskeletal Diseases

Pengbin Yin, Yuheng Jiang, Xuan Fang, Daofeng Wang, Yi Li, Ming Chen, Hao Deng, Peifu Tang, Licheng Zhang

Adv Sci (Weinh) 2023 Jul; 10(21): 2207050. Published online 2023 May 18. doi: 10.1002/advs.202207050

PMCID:: PMC10375105

Abstract Article PDF–1.4M

Select item 98983706.

Cell-based therapies have disease-modifying effects on osteoarthritis in animal models. A systematic review by the ESSKA Orthobiologic Initiative. Part 1: adipose tissue-derived cell-based injectable therapies

Carlotta Perucca Orfei, Angelo Boffa, Yosef Sourugeon, Lior Laver, Jérémy Magalon, Mikel Sánchez, Thomas Tischer, Giuseppe Filardo, Laura de Girolamo

Knee Surg Sports Traumatol Arthrosc. 2023; 31(2): 641–655. Published online 2022 Sep 14. doi: 10.1007/s00167-022-07063-7

PMCID:: PMC9898370

Abstract Article PDF–1.5M

Select item 93652397.

Regenerative Engineering Animal Models for Knee Osteoarthritis

Caldon Jayson Esdaille, Chinedu Cletus Ude, Cato T. Laurencin

Regen Eng Transl Med. Author manuscript; available in PMC 2022 Aug 10.

Published in final edited form as: Regen Eng Transl Med. 2022 Jun; 8(2): 284–297. Published online 2021 Jul 29. doi: 10.1007/s40883-021-00225-y

PMCID:: PMC9365239

Abstract Article PDF–826K

Select item 93172688.

Effects of Combined Allogenic Adipose Stem Cells and Hyperbaric Oxygenation Treatment on Pathogenesis of Osteoarthritis in Knee Joint Induced by Monoiodoacetate

Aleksandar Juskovic, Marina Nikolic, Biljana Ljujic, Aleksandar Matic, Vladimir Zivkovic, Ksenija Vucicevic, Zoran Milosavljevic, Radisa Vojinovic, Nemanja Jovicic, Suzana Zivanovic, Nevena Milivojevic, Vladimir Jakovljevic, Sergey Bolevich, Marina Miletic Kovacevic

Int J Mol Sci. 2022 Jul; 23(14): 7695. Published online 2022 Jul 12. doi: 10.3390/ijms23147695

PMCID:: PMC9317268

Abstract Article PDF–2.1M

Select item 89861329.

Regenerative Engineering for Knee Osteoarthritis Treatment: Biomaterials and Cell-Based Technologies

Jorge L. Escobar Ivirico, Maumita Bhattacharjee, Emmanuel Kuyinu, Lakshmi S. Nair, Cato T. Laurencin

Engineering (Beijing) Author manuscript; available in PMC 2022 Apr 6.

Published in final edited form as: Engineering (Beijing). 2017 Feb; 3(1): 16–27. Published online 2017 Feb 14. doi: 10.1016/j.eng.2017.01.003

PMCID:: PMC8986132

Abstract Article PDF–847K

Select item 893428210.

Mechanism of action of mesenchymal stem cells (MSCs): Impact of Delivery Method

Luiza L. Bagno, Alessandro G. Salerno, Wayne Balkan, Joshua M. Hare

Expert Opin Biol Ther. Author manuscript; available in PMC 2023 Apr 1.

Published in final edited form as: Expert Opin Biol Ther. 2022 Apr; 22(4): 449–463. Published online 2021 Dec 27. doi: 10.1080/14712598.2022.2016695

PMCID:: PMC8934282

Abstract Article PDF–1.3M

Select item 879477611.

Injectable amnion hydrogel-mediated delivery of adipose-derived stem cells for osteoarthritis treatment

Maumita Bhattacharjee, Jorge L. Escobar Ivirico, Ho-Man Kan, Shiv Shah, Takayoshi Otsuka, Rosalie Bordett, Mohammed Barajaa, Naveen Nagiah, Rishikesh Pandey, Lakshmi S. Nair, Cato T. Laurencin

Proc Natl Acad Sci U S A. 2022 Jan 25; 119(4): e2120968119. Published online 2022 Jan 19. doi: 10.1073/pnas.2120968119

PMCID:: PMC8794776

Abstract Article PDF–2.0M

Select item 786883512.

Allogeneic adipose-derived mesenchymal stem cells promote the expression of chondrocyte redifferentiation markers and retard the progression of knee osteoarthritis in rabbits

Rui Zhang, Fanbo Meng, Qiaoxia Zhang, Zhiyu Zou, Kunlin Xiao, Tian Zhu, Hui Li, Weijie Zhang, Jie Ma, Jianbing Ma

Am J Transl Res. 2021; 13(2): 632–645. Published online 2021 Feb 15.

PMCID:: PMC7868835

Abstract Article PDF–2.5M

Select item 766465513.

Application of Mesenchymal Stem Cells in Inflammatory and Fibrotic Diseases

Jae-Sung Ryu, Eun-Jeong Jeong, Jong-Yeup Kim, Soon Ju Park, Won Seok Ju, Chang-Hyun Kim, Jang-Seong Kim, Young-Kug Choo

Int J Mol Sci. 2020 Nov; 21(21): 8366. Published online 2020 Nov 7. doi: 10.3390/ijms21218366

PMCID:: PMC7664655

Abstract Article PDF–731K

Select item 754918714.

THERAPEUTIC EFFICACY OF INTRA-ARTICULAR DELIVERY OF ENCAPSULATED HUMAN MESENCHYMAL STEM CELLS ON EARLY STAGE OSTEOARTHRITIS

J.M. McKinney, T.N. Doan, L. Wang, J.N. Deppen, D.S. Reece, K.A. Pucha, S.C. Ginn, R.D. Levit, N.J. Willett

Eur Cell Mater. Author manuscript; available in PMC 2020 Oct 12.

Published in final edited form as: Eur Cell Mater. 2019 Jan 29; 37: 42–59. Published online 2019 Jan 29. doi: 10.22203/eCM.v037a04

PMCID:: PMC7549187

Abstract Article PDF–2.7M

Select item 664253115.

Intraarticular injection of processed lipoaspirate cells has anti-inflammatory and analgesic effects but does not improve degenerative changes in murine monoiodoacetate-induced osteoarthritis

Takumi Sakamoto, Tsuyoshi Miyazaki, Shuji Watanabe, Ai Takahashi, Kazuya Honjoh, Hideaki Nakajima, Hisashi Oki, Yasuo Kokubo, Akihiko Matsumine

BMC Musculoskelet Disord. 2019; 20: 335. Published online 2019 Jul 19. doi: 10.1186/s12891-019-2710-1

PMCID:: PMC6642531

Abstract Article PDF–2.6M

Select item 650346016.

Application of mesenchymal stem cell therapy for the treatment of osteoarthritis of the knee: A concise review

Ai-Tong Wang, Ying Feng, Hong-Hong Jia, Meng Zhao, Hao Yu

World J Stem Cells. 2019 Apr 26; 11(4): 222–235. Published online 2019 Apr 26. doi: 10.4252/wjsc.v11.i4.222

PMCID:: PMC6503460

Abstract Article PDF–625K

Select item 639236717.

Umbilical Cord‐Derived Mesenchymal Stromal Cells (MSCs) for Knee Osteoarthritis: Repeated MSC Dosing Is Superior to a Single MSC Dose and to Hyaluronic Acid in a Controlled Randomized Phase I/II Trial

Jose Matas, Mario Orrego, Diego Amenabar, Catalina Infante, Rafael Tapia‐Limonchi, Maria Ignacia Cadiz, Francisca Alcayaga‐Miranda, Paz L. González, Emilio Muse, Maroun Khoury, Fernando E. Figueroa, Francisco Espinoza

Stem Cells Transl Med. 2019 Mar; 8(3): 215–224. Published online 2018 Dec 28. doi: 10.1002/sctm.18-0053