Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Inhibition of TRPC7 channel (unknown origin) expressed in HEK293 cells assessed as inhibition of GSK1702934A-evoked Ca2+ entry by measuring reduction in intracellular Ca2+ level by Fluo-4 dye based FLIPR assay
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of TRPC6 channel (unknown origin) expressed in HEK293 cells assessed as inhibition of OAG-evoked Ca2+ entry by measuring reduction in intracellular Ca2+ level by Fluo-4 dye based FLIPR assay
Inhibition of human TRPC3 channel expressed in HEK293 cells assessed as inhibition of OAG-evoked Ca2+ entry by measuring reduction in intracellular Ca2+ level by Fluo-4 dye based FLIPR assay
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of human TRPC6 expressed in HEK293F cells assessed as inhibition of carbachol-induced calcium response up to 20 uM
Electrophysiology Assay from US Patent US11274091: "Cyclopentane compounds"
Assay data:32 Active, 32 Activity ≤ 1 µM, 32 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
High Throughput Screening Assay from US Patent US10889568: "Inhibitors of TRPC6"
Assay data:95 Active, 87 Activity ≤ 1 µM, 95 Tested
High Throughput Screening Assay from US Patent US10800757: "Inhibitors of TRPC6"
Assay data:94 Active, 86 Activity ≤ 1 µM, 94 Tested
TRP selectivity screen (TRPC6)
Assay data:2 Tested
SummaryRelated BioAssays by Target
TRP selectivity screen (TRPC3)
Antagonist activity at human TRPC6 at <= 30 uM
Antagonist activity at human TRPC3 at <= 30 uM
Inhibition of human TRPC6 channel transfected in HEK293 cells assessed as intracellular calcium level by FLIPR assay
Assay data:6 Active, 6 Activity ≤ 1 nM, 6 Activity ≤ 1 µM, 6 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of mouse TRPC3 expressed in HEK293 cells assessed as inhibition of Ca2+ influx by whole cell patch-clamp method
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Inhibition of human TRPC7 expressed in HEK293 cells assessed as inhibition of GSK170-induced current at 10 uM by whole cell patch-clamp method
Inhibition of mouse TRPC6 expressed in HEK293 cells assessed as inhibition of GSK170-induced current at 10 uM by whole cell patch-clamp method
Inhibition of human TRPC3 expressed in HEK293 cells assessed as inhibition of OAG-induced current at 0.001 to 10 uM by whole cell patch-clamp method
Assay data:2 Active, 2 Tested
Inhibition of human TRPC3 expressed in HEK293 cells assessed as inhibition of GSK170-induced current in presence of 2 mM extracellular calcium by whole cell patch-clamp method
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
Inhibition of human TRPC3 expressed in HEK293 cells assessed as inhibition of GSK170-induced current in absence of extracellular calcium by whole cell patch-clamp method
Inhibition of human TRPC3 expressed in HEK293 cells assessed as inhibition of GSK170-induced current at 10 uM in absence of extracellular calcium by whole cell patch-clamp method relative to control
Assay data:9 Tested
Inhibition of TRPC7 channel (unknown origin)
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on