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K+V channel CEREP ligand profiling
Assay data:1 Tested
SummaryRelated BioAssays by Target
K+ channel (volt-dependent) CEREP ligand profiling
K+ channel (Volt-dependent) Ligand binding assay
K+ channel (Volt-dependent) CEREP screen
Inhibition of human Kv1.6 at 100 uM
Assay data:2 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of Kv1.6 (unknown origin) at 3 uM relative to control
RNAi screen for vemurafenib enhancer genes in BRAFV600 melanoma - Primary Screen
Assay data:790 Active, 18119 Tested
Summary
Inhibition of human Kv1.6 expressed in CHO cells at -80 mV holding potential by whole cell automated patch clamp method
Assay data:5 Active, 1 Activity ≤ 1 µM, 11 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Binding affinity to voltage-gated potassium channel (unknown origin) at 10 uM relative to control
Human Kv1.6 (Voltage-gated potassium channels)
Assay data:4 Active, 4 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Binding affinity to voltage-gated potassium channel (unknown origin) at 10 uM by radioligand binding assay
Displacement of [125-I]-dendrotoxin from Kv channel (unknown origin) at 0.1 to 10 mM
Binding affinity to potassium channel (unknown origin) assessed as inhibition of control specific binding at 10 uM
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced TNF-alpha response in human macrophages_Primary screen TNF readout
Assay data:2853 Active, 18113 Tested
SummaryRelated BioAssays by Same Project
A screen to identify synthetic lethal interactions with E-cadherin in an MCF10A isogenic cell line
Assay data:2442 Active, 18052 Tested
SummaryPubMed Citation
A screen to identify genes that regulate lymphatic endothelial cell migration - Primary Screen
Assay data:1034 Active, 18120 Tested
SummaryRelated BioAssays by Depositor
Identification of proteins required for the processing of the EWS-FLI1 nascent transcript
Assay data:59220 Tested
InfectX: Pathogen infection siRNA screens
Assay data:115372 Tested
A whole genome RNAi screen highlights components of the ER/Golgi as a prominent source of resistance to immunotoxin-mediated cytotoxicity
Assay data:555 Active, 64752 Tested
Inhibition of human Kv channel at 1 uM relative to control
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