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Antibacterial activity against Bacillus anthracis Ames 35 after 20 hrs by broth microdilution assay
Assay data:9 Active, 2 Activity ≤ 1 µM, 9 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Antibacterial activity against Bacillus anthracis Ames NR-3838 by two fold serial dilution method
Assay data:8 Active, 1 Activity ≤ 1 µM, 12 Tested
Antimicrobial activity against Bacillus anthracis AMES
Assay data:1 Active, 1 Activity ≤ 1 µM, 3 Tested
Antimicrobial activity against Bacillus anthracis Ames after 24 hrs
Assay data:13 Active, 8 Activity ≤ 1 µM, 25 Tested
Antibacterial activity against Bacillus anthracis Ames infected in BALB/c mouse assessed as decrease in bacterial load in lungs at 30 mg/kg, ip administered 24 hrs postinfection at 12 hrs interval for 14 days measured on day 27
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed Citation
Antibacterial activity against Bacillus anthracis Ames infected in BALB/c mouse assessed as decrease in bacterial load in lungs at 20 mg/kg, ip administered 24 hrs postinfection at 4 hrs interval for 14 days measured on day 27
Antimicrobial activity against Bacillus anthracis Ames infected in BALB/c mouse anthrax spore inhalation infection model assessed as decrease in tissue bacterial burden at 30 mg/kg, ip bid for 21 days administered 24 hrs post bacterial challenge measured 43 days post bacterial challenge
Antimicrobial activity against Bacillus anthracis Ames infected in BALB/c mouse anthrax spore inhalation infection model assessed as decrease in tissue bacterial burden at 30 mg/kg, ip bid for 14 days administered 24 hrs post bacterial challenge measured 43 days post bacterial challenge
Antimicrobial activity against Bacillus anthracis Ames infected in BALB/c mouse anthrax spore inhalation infection model assessed as decrease in tissue bacterial burden at 50 mg/kg, sc bid for 21 days administered 24 hrs post bacterial challenge measured 43 days post bacterial challenge
Antimicrobial activity against Bacillus anthracis Ames infected in BALB/c mouse anthrax spore inhalation infection model assessed as decrease in tissue bacterial burden at 50 mg/kg, sc bid for 14 days administered 24 hrs post bacterial challenge measured 43 days post bacterial challenge
Antibacterial activity against Bacillus anthracis Ames expressing FabI assessed as growth inhibition after 18 to 24 hrs by microdilution method
Assay data:4 Tested
SummaryPubMed Citation
Antimicrobial activity against Bacillus anthracis Ames by broth microdilution method in presence of polysorbate-80
Assay data:1 Tested
Antibacterial activity against Bacillus anthracis Ames spores infected in C57BL/6 mouse assessed as protection against microbe-induced mortality at 10 mg/kg, ip for 5 days every 6 hrs administered 18 to 24 hrs postinfection and measured upto 20 days postinfection
Antibacterial activity against Bacillus anthracis Ames spores infected in C57BL/6 mouse assessed as mouse survival rate at 1 mg/kg, ip for 5 days every 6 hrs administered 6 hrs post bacterial challenge measured up to 20 days post infection
Antibacterial activity against Bacillus anthracis Ames spores infected in C57BL/6 mouse assessed as mouse survival rate at 10 mg/kg, ip for 5 days every 6 hrs administered 6 hrs post bacterial challenge measured up to 20 days post infection
Antimicrobial activity against Bacillus anthracis Ames by broth microdilution method in presence of 10% fetal calf serum
Antimicrobial activity against ciprofloxacin-resistant Bacillus anthracis Ames 105-6 by broth microdilution method
Assay data:5 Tested
Antimicrobial activity against Bacillus anthracis Ames spores by broth microdilution method
Antimicrobial activity against Bacillus anthracis Ames by broth microdilution method
Assay data:2 Tested
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