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Items: 5

1.

Retinal Detachment

Separation of the inner layers of the retina (neural retina) from the pigment epithelium. Retinal detachment occurs more commonly in men than in women, in eyes with degenerative myopia, in aging and in aphakia. It may occur after an uncomplicated cataract extraction, but it is seen more often if vitreous humor has been lost during surgery. (Dorland, 27th ed; Newell, Ophthalmology: Principles and Concepts, 7th ed, p310-12).

2.

Knobloch syndrome [Supplementary Concept]

Date introduced: August 25, 2010

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Rhegmatogenous Retinal Detachment, Autosomal Dominant [Supplementary Concept]

A hereditary autosomal dominant disorder characterized by retinal detachment due to retinal tearing at the time of posterior vitreous detachment and PATHOLOGICAL MYOPIA. It is often described as a feature of Stickler Syndrome (OMIM: 108300) or erosive vitreoretinopathy (OMIM: 143200). However affected individuals with DRRD alone do not exhibit the vitreous phenotypes associated with Stickler Syndrome and show no signs of skeletal dysplasia or deafness. Mutations in the COL2A1 gene have been identified. OMIM: 609508

Date introduced: November 5, 2012

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