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Items: 5

1.

Propofol

An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.

Year introduced: 1990

2.

Propofol Infusion Syndrome

Rare and often fatal drug complication which affects patients undergoing long-term treatment with high doses of PROPOFOL. It is characterized by METABOLIC ACIDOSIS; HYPERLIPIDEMIA; RHABDOMYOLYSIS; cardiovascular CIRCULATORY COLLAPSE; CARDIAC FAILURE; and KIDNEY FAILURE.

Year introduced: 2017

3.

propofol hydroxypropyl-beta-cyclodextrin [Supplementary Concept]

a propofol inclusion complex

Date introduced: November 1, 1993

4.

propofol stearate [Supplementary Concept]

an anticancer stearic acid-based ester conjugate; structure in first source

Date introduced: August 12, 2013

5.

2,6-diisopropyl-4-(3-(3-methyl-3H-diazirin-3-yl)propyl)phenol [Supplementary Concept]

a photoreactive general anesthetic; structure in first source

Date introduced: March 1, 2012

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