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1.

Candida

A genus of yeast-like mitosporic Saccharomycetales fungi characterized by producing yeast cells, mycelia, pseudomycelia, and blastophores. It is commonly part of the normal flora of the skin, mouth, intestinal tract, and vagina, but can cause a variety of infections, including CANDIDIASIS; ONYCHOMYCOSIS; VULVOVAGINAL CANDIDIASIS; and CANDIDIASIS, ORAL (THRUSH).

2.

Candida glabrata

A species of MITOSPORIC FUNGI commonly found on the body surface. It causes opportunistic infections especially in immunocompromised patients.

Year introduced: 2003

3.

Candida tropicalis

A species of MITOSPORIC FUNGI that is a major cause of SEPTICEMIA and disseminated CANDIDIASIS, especially in patients with LYMPHOMA; LEUKEMIA; and DIABETES MELLITUS. It is also found as part of the normal human mucocutaneous flora.

Year introduced: 2003

4.

Candida albicans

A unicellular budding fungus which is the principal pathogenic species causing CANDIDIASIS (moniliasis).

Year introduced: 1973(1972)

5.

Candida auris

A species of yeast in genus Candida. C. auris infection is most often associated with immunocompromised patients in healthcare settings. INVASIVE CANDIDIASIS and colonization pose a treatment challenge when multidrug resistant strains are involved.

Year introduced: 2022(2018)

6.

Candida parapsilosis

A species of MITOSPORIC FUNGI and opportunistic pathogen associated with its ability to form BIOFILMS in catheters and parenteral nutrition IV lines. C. parapsilosis complex includes closely related species C. orthopsilosis; and C. metapsilosis.

Year introduced: 2018

7.

CYP52A3 protein, Candida maltosa [Supplementary Concept]

an alkane hydroxylase; catalyzes the complete oxidation of n-alkanes to alpha, omega-dioic acids

Date introduced: January 7, 1999

8.

PHR1 protein, Candida albicans [Supplementary Concept]

Required for apical cell growth and plays an essential role in morphogenesis; may be integral to the pathogenic ability of the organism; PHR1 regulated by pH; 56% identical to Ggp1/Gas1 protein from Saccharomyces cerevisiae; amino acid sequence in first source; GenBank M90812 (PHR1)

Date introduced: February 13, 1995

9.

alphaINT1 protein, Candida albicans [Supplementary Concept]

contains integrin motifs; isolated from Candida albicans; has been sequenced; GenBank U35070

Date introduced: February 19, 1996

10.

UDP-glucose 4,6-dehydratase, Candida albicans [Supplementary Concept]

affects virulence and cell wall mannan composition

Date introduced: March 22, 2012

11.

ALA1 protein, Candida albicans [Supplementary Concept]

from Candida albicans; confers adherence properties upon Saccharomyces cerevisiae for extracellular matrix proteins; homologous to ALS1 gene product; amino acid sequence in first source; GenBank AF025429

Date introduced: December 30, 1997

12.

Meyerozyma carpophila [Supplementary Concept]

Date introduced: October 1, 2020

13.

Candidiasis

Infection with a fungus of the genus CANDIDA. It is usually a superficial infection of the moist areas of the body and is generally caused by CANDIDA ALBICANS. (Dorland, 27th ed)

Year introduced: 1981

14.

RIM101 protein, Candida albicans [Supplementary Concept]

amino acid sequence given in first source; a single-stranded DNA-binding protein required for mitochondrial DNA replication in yeast; homologous to E. coli SSB; RIM stands for replication in mitochondria

Date introduced: September 29, 2004

15.

CBF1 protein, Candida albicans [Supplementary Concept]

GenBank AJ303083

Date introduced: February 14, 2004

16.
17.

lipase B, Candida antarctica [Supplementary Concept]

a serine hydrolase which displays enantioselectivity towards secondary alcohols; GenBank Z30645

Date introduced: July 25, 2001

18.

CGR1 protein, Candida albicans [Supplementary Concept]

regulated during the yeast-hyphal transition in Candida albicans; amino acid sequence in first source

Date introduced: May 21, 2001

19.

PMP32 protein, Candida boidinii [Supplementary Concept]

isolated from Candida boidinii; amino acid sequence in first source; GenBank L28000

Date introduced: March 26, 1995

20.

PMP31 protein, Candida boidinii [Supplementary Concept]

isolated from Candida boidinii; amino acid sequence in first source; GenBank L27999

Date introduced: March 26, 1995

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