Kleine-Levin Syndrome

A rare condition characterized by recurrent hypersomnias associated with hyperphagia, occurring primarily in males in the second to third decade of life. Clinical features include mental confusion, excessive sleep requirements (approximately 18 hours per day), restlessness, and in some cases hallucinations. Episodes have a duration of days to weeks, and may recur several times per year. This condition may resolve spontaneously over several years. (From Adams, et al., Principles of Neurology, 6th ed, p569)

Year introduced: 1994

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Do not include MeSH terms found below this term in the MeSH hierarchy.

Tree Number(s): C10.886.425.800.200.500, F03.870.400.800.200.500

MeSH Unique ID: D017593

Entry Terms:

• Kleine Levin Syndrome
• Syndrome, Kleine-Levin
• Hypersomnia, Periodic
• Periodic Hypersomnia
• Periodic Hypersomnias
• Kleine-Levin Hibernation Syndrome
• Hibernation Syndrome, Kleine-Levin
• Kleine Levin Hibernation Syndrome
• Syndrome, Kleine-Levin Hibernation
• Kleine-Levin-Critchley Syndrome
• Kleine Levin Critchley Syndrome
• Syndrome, Kleine-Levin-Critchley
• Familial Kleine-Levin Syndrome
• Familial Kleine Levin Syndrome
• Kleine-Levin Syndrome, Familial
• Syndrome, Familial Kleine-Levin
• Familial Hibernation (Kleine-Levin) Syndrome

Previous Indexing:

• Eating Disorders (1966-1976)
• Hunger (1966-1971)
• Hyperphagia (1981-1993)
• Hypersomnia (1975-1993)
• Sleep Disorders (1966-1979)

All MeSH Categories
Diseases Category
Nervous System Diseases
Sleep Wake Disorders
Dyssomnias
Sleep Disorders, Intrinsic
Disorders of Excessive Somnolence
Kleine-Levin Syndrome

All MeSH Categories
Psychiatry and Psychology Category
Mental Disorders
Sleep Wake Disorders
Dyssomnias
Sleep Disorders, Intrinsic
Disorders of Excessive Somnolence
Kleine-Levin Syndrome