Sodium Channel Blockers

A class of drugs that act by inhibition of sodium influx through cell membranes. Blockade of sodium channels slows the rate and amplitude of initial rapid depolarization, reduces cell excitability, and reduces conduction velocity.

Year introduced: 2002

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Tree Number(s): D27.505.519.562.750, D27.505.954.411.720

MeSH Unique ID: D026941

Entry Terms:

• Channel Blockers, Sodium
• Sodium Channel Inhibitors
• Channel Inhibitors, Sodium
• Inhibitors, Sodium Channel
• Sodium Channel Blocker
• Blocker, Sodium Channel
• Channel Blocker, Sodium
• Sodium Channel Inhibitor
• Channel Inhibitor, Sodium
• Inhibitor, Sodium Channel

Previous Indexing:

• Ion Channels (1982-1988)
• Sodium Channels/antagonists and inhibitors (1988-2001)

See Also:

• Anti-Arrhythmia Agents

All MeSH Categories
Chemicals and Drugs Category
Chemical Actions and Uses
Pharmacologic Actions
Molecular Mechanisms of Pharmacological Action
Membrane Transport Modulators
Sodium Channel Blockers
Acid Sensing Ion Channel Blockers
Epithelial Sodium Channel Blockers
Voltage-Gated Sodium Channel Blockers

All MeSH Categories
Chemicals and Drugs Category
Chemical Actions and Uses
Pharmacologic Actions
Therapeutic Uses
Cardiovascular Agents
Sodium Channel Blockers
Voltage-Gated Sodium Channel Blockers