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Dopamine Antagonists

Drugs that bind to but do not activate DOPAMINE RECEPTORS, thereby blocking the actions of dopamine or exogenous agonists. Many drugs used in the treatment of psychotic disorders (ANTIPSYCHOTIC AGENTS) are dopamine antagonists, although their therapeutic effects may be due to long-term adjustments of the brain rather than to the acute effects of blocking dopamine receptors. Dopamine antagonists have been used for several other clinical purposes including as ANTIEMETICS, in the treatment of Tourette syndrome, and for hiccup. Dopamine receptor blockade is associated with NEUROLEPTIC MALIGNANT SYNDROME.

Year introduced: 1995

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Subheadings:

Tree Number(s): D27.505.519.625.150.175, D27.505.696.577.150.175

MeSH Unique ID: D018492

Entry Terms:

  • Dopamine Receptor Antagonists
  • Receptor Antagonists, Dopamine
  • Dopaminergic Antagonists
  • Antagonists, Dopamine
  • Antagonists, Dopamine Receptor
  • Antagonists, Dopaminergic
  • Dopamine Blockers
  • Blockers, Dopamine
  • Dopamine Antagonist
  • Antagonist, Dopamine
  • Dopamine Blocker
  • Blocker, Dopamine
  • Dopamine Receptor Antagonist
  • Antagonist, Dopamine Receptor
  • Receptor Antagonist, Dopamine
  • Dopaminergic Antagonist
  • Antagonist, Dopaminergic

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