Neurotransmitter Uptake Inhibitors

Drugs that inhibit the transport of neurotransmitters into axon terminals or into storage vesicles within terminals. For many transmitters, uptake determines the time course of transmitter action so inhibiting uptake prolongs the activity of the transmitter. Blocking uptake may also deplete available transmitter stores. Many clinically important drugs are uptake inhibitors although the indirect reactions of the brain rather than the acute block of uptake itself is often responsible for the therapeutic effects.

Year introduced: 1993

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Do not include MeSH terms found below this term in the MeSH hierarchy.

Tree Number(s): D27.505.519.562.437, D27.505.519.625.600, D27.505.696.577.600

MeSH Unique ID: D014179

Entry Terms:

• Inhibitors, Neurotransmitter Uptake
• Uptake Inhibitors, Neurotransmitter
• Transmitter Uptake Inhibitors, Neuronal
• Reuptake Inhibitors, Neurotransmitter
• Inhibitors, Neurotransmitter Reuptake
• Neurotransmitter Reuptake Inhibitors

Previous Indexing:

• Cytoplasmic Granules (1966-1977)
• Kinetics (1966-1984)
• Nerve Endings (1966-1973)
• Synapses (1966-1971)
• Synaptic Vesicles (1972-1973)
• Synaptosomes (1974-1984)

All MeSH Categories
Chemicals and Drugs Category
Chemical Actions and Uses
Pharmacologic Actions
Molecular Mechanisms of Pharmacological Action
Membrane Transport Modulators
Neurotransmitter Uptake Inhibitors
Adrenergic Uptake Inhibitors
Dopamine Uptake Inhibitors
GABA Uptake Inhibitors
Selective Serotonin Reuptake Inhibitors
Serotonin and Noradrenaline Reuptake Inhibitors

All MeSH Categories
Chemicals and Drugs Category
Chemical Actions and Uses
Pharmacologic Actions
Molecular Mechanisms of Pharmacological Action
Neurotransmitter Agents
Neurotransmitter Uptake Inhibitors
Adrenergic Uptake Inhibitors
Dopamine Uptake Inhibitors
GABA Uptake Inhibitors
Selective Serotonin Reuptake Inhibitors
Serotonin and Noradrenaline Reuptake Inhibitors

All MeSH Categories
Chemicals and Drugs Category
Chemical Actions and Uses
Pharmacologic Actions
Physiological Effects of Drugs
Neurotransmitter Agents
Neurotransmitter Uptake Inhibitors
Adrenergic Uptake Inhibitors
Dopamine Uptake Inhibitors
GABA Uptake Inhibitors
Selective Serotonin Reuptake Inhibitors
Serotonin and Noradrenaline Reuptake Inhibitors