Pentostatin
A potent inhibitor of ADENOSINE DEAMINASE. The drug induces APOPTOSIS of LYMPHOCYTES, and is used in the treatment of many lymphoproliferative malignancies, particularly HAIRY CELL LEUKEMIA. It is also synergistic with some other antineoplastic agents and has immunosuppressive activity.
Year introduced: 1997 (1990)
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Tree Number(s): D03.383.742.680.350.200.700, D13.570.230.677, D13.570.685.350.200.700
MeSH Unique ID: D015649
Registry Number: 395575MZO7
Entry Terms:
- NSC-218321
- NSC218321
- NSC 218321
- CI-825
- CI825
- CI 825
- Nipent
- Co-Vidarabine
- Deoxycoformycin
- Imidazo(4,5-d)(1,3)diazepin-8-ol, 3-(2-deoxy-beta-D-erythro-pentofuranosyl)-3,4,7,8-tetrahydro-, (R)-
- 2'-Deoxycoformycin
- 2' Deoxycoformycin
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