Complement C4b

The large fragment formed when COMPLEMENT C4 is cleaved by COMPLEMENT C1S. The membrane-bound C4b binds COMPLEMENT C2A, a SERINE PROTEASE, to form C4b2a (CLASSICAL PATHWAY C3 CONVERTASE) and subsequent C4b2a3b (CLASSICAL PATHWAY C5 CONVERTASE).

Year introduced: 2006 (1990)

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Tree Number(s): D12.776.124.486.274.350.260

MeSH Unique ID: D015935

Registry Number: 80295-50-7

Entry Terms:

• C4b, Complement
• C4b Complement
• Complement, C4b
• Complement 4b
• Complement Component 4b
• Component 4b, Complement

Previous Indexing:

• Complement 4 (1975-1989)

Pharmacologic Action:

• Immunologic Factors

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Proteins
Blood Proteins
Immunoproteins
Complement System Proteins
Complement C4
Complement C4b