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Globosides

Glycosphingolipids containing N-acetylglucosamine (paragloboside) or N-acetylgalactosamine (globoside). Globoside is the P antigen on erythrocytes and paragloboside is an intermediate in the biosynthesis of erythrocyte blood group ABH and P 1 glycosphingolipid antigens. The accumulation of globoside in tissue, due to a defect in hexosaminidases A and B, is the cause of Sandhoff disease.

Year introduced: 1991(1979)

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Subheadings:

Tree Number(s): D02.065.313.425, D09.400.410.420.525.200.425, D10.390.470.675.200.425, D10.570.877.360.612.200.425

MeSH Unique ID: D005915

Entry Terms:

  • Cytolipins
  • Lacto-N-neotetraosylceramide
  • Lacto N neotetraosylceramide
  • Lacto-N-tetraosylceramide
  • Lacto N tetraosylceramide
  • Lactoneotetraosylceramide

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