SRS-A

A group of LEUKOTRIENES; (LTC4; LTD4; and LTE4) that is the major mediator of BRONCHOCONSTRICTION; HYPERSENSITIVITY; and other allergic reactions. Earlier studies described a slow-reacting substance of ANAPHYLAXIS released from lung by cobra venom or after anaphylactic shock. The relationship between SRS-A leukotrienes was established by UV which showed the presence of the conjugated triene. (From Merck Index, 11th ed)

Year introduced: 1973(1967)

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Tree Number(s): D10.251.355.255.100.450.855, D10.251.355.310.166.887.855, D23.469.050.175.450.725

MeSH Unique ID: D013189

Entry Terms:

• Slow Reacting Substance of Anaphylaxis

Previous Indexing:

• Anaphylaxis (1966)
• Muscle, Smooth/physiology (1966)

All MeSH Categories
Chemicals and Drugs Category
Lipids
Fatty Acids
Fatty Acids, Unsaturated
Eicosanoids
Arachidonic Acids
Leukotrienes
SRS-A
Leukotriene C4
Leukotriene D4
Leukotriene E4

All MeSH Categories
Chemicals and Drugs Category
Lipids
Fatty Acids
Fatty Acids, Unsaturated
Fatty Acids, Essential
Arachidonic Acids
Leukotrienes
SRS-A
Leukotriene C4
Leukotriene D4
Leukotriene E4

All MeSH Categories
Chemicals and Drugs Category
Biological Factors
Inflammation Mediators
Autacoids
Eicosanoids
Leukotrienes
SRS-A
Leukotriene C4
Leukotriene D4
Leukotriene E4