2',5'-Oligoadenylate Synthetase

An enzyme that catalyzes the conversion of ATP into a series of (2'-5') linked oligoadenylates and pyrophosphate in the presence of double-stranded RNA. These oligonucleotides activate an endoribonuclease (RNase L) which cleaves single-stranded RNA. Interferons can act as inducers of these reactions.

Year introduced: 1983

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Tree Number(s): D08.811.913.696.445.625

MeSH Unique ID: D015088

Registry Number: EC 2.7.7.84

Entry Terms:

• 2',5' Oligoadenylate Synthetase
• Synthetase, 2',5'-Oligoadenylate
• (2'-5')An Polymerase
• 2',5'-Oligo(A) Polymerase
• 2-5A Synthetase
• ATP-(2'-5')oligo(A)adenylyltransferase
• 2',5'-Oligo(A) Synthetase
• 2,5 Oligoadenylate Polymerase
• Oligoadenylate Polymerase, 2,5
• Polymerase, 2,5 Oligoadenylate
• 2,5 Oligoadenylate Synthetase
• Oligoadenylate Synthetase, 2,5
• Synthetase, 2,5 Oligoadenylate
• 2',5'-Oligoadenylate Polymerase
• 2',5' Oligoadenylate Polymerase
• Polymerase, 2',5'-Oligoadenylate

Previous Indexing:

• Nucleotidyltransferases (1966-1982)

All MeSH Categories
Chemicals and Drugs Category
Enzymes and Coenzymes
Enzymes
Transferases
Phosphotransferases
Nucleotidyltransferases
2',5'-Oligoadenylate Synthetase