DNA Polymerase I
A DNA-dependent DNA polymerase characterized in prokaryotes and may be present in higher organisms. It has both 3'-5' and 5'-3' exonuclease activity, but cannot use native double-stranded DNA as template-primer. It is not inhibited by sulfhydryl reagents and is active in both DNA synthesis and repair.
Year introduced: 1984(1977)
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Subheadings:
Tree Number(s): D08.811.913.696.445.308.300.225
MeSH Unique ID: D004256
Registry Number: EC 2.7.7.7
Entry Terms:
- DNA Pol I
- DNA Polymerase alpha
- Polymerase alpha, DNA
- DNA-Dependent DNA Polymerase I
- DNA Dependent DNA Polymerase I
- Klenow Fragment
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