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Cytochrome P-450 CYP2E1

An ethanol-inducible cytochrome P450 enzyme that metabolizes several precarcinogens, drugs, and solvents to reactive metabolites. Substrates include ETHANOL; INHALATION ANESTHETICS; BENZENE; ACETAMINOPHEN and other low molecular weight compounds. CYP2E1 has been used as an enzyme marker in the study of alcohol abuse.

Year introduced: 1997

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Subheadings:

Tree Number(s): D08.244.453.491.375, D08.811.682.662.582.338, D08.811.682.690.708.170.450.375, D12.776.422.220.453.491.375

MeSH Unique ID: D019392

Registry Number: EC 1.14.13.-

Entry Terms:

  • Cytochrome P 450 CYP2E1
  • CYPIIE1
  • N-Nitrosodimethylamine Demethylase
  • N Nitrosodimethylamine Demethylase
  • Cytochrome P-450 (ALC)
  • Cytochrome P-450-J
  • Cytochrome P 450 J
  • 4-Nitrophenol-2-Hydroxylase
  • 4 Nitrophenol 2 Hydroxylase
  • Dimethylnitrosamine N-Demethylase
  • Dimethylnitrosamine N Demethylase
  • Cytochrome P450 2E1
  • CYP2E1
  • CYP 2E1
  • CYP IIE1
  • Cytochrome P-450 IIE1
  • Cytochrome P 450 IIE1

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