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Iron Regulatory Protein 2

A multifunctional iron-sulfur protein that is both an iron regulatory protein and cytoplasmic form of aconitate hydratase. It binds to iron regulatory elements found on mRNAs involved in iron metabolism and regulates their translation. Its rate of degradation is increased in the presence of IRON.

Year introduced: 2003

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Subheadings:

Tree Number(s): D08.811.520.241.300.050.750, D12.776.157.427.374.375.961, D12.776.157.725.437, D12.776.494.750, D12.776.556.579.374.375.962, D12.776.664.962.437

MeSH Unique ID: D035942

Registry Number: EC 4.2.1.3

Entry Terms:

  • IRE-BP2
  • IRP-2 RNA-binding protein
  • IRP 2 RNA binding protein
  • RNA-binding protein, IRP-2
  • IRP2 Protein
  • Iron-Responsive-Element Binding Protein 2
  • IREB2 Protein

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