Pyruvate Decarboxylase

Catalyzes the decarboxylation of an alpha keto acid to an aldehyde and carbon dioxide. Thiamine pyrophosphate is an essential cofactor. In lower organisms, which ferment glucose to ethanol and carbon dioxide, the enzyme irreversibly decarboxylates pyruvate to acetaldehyde. EC 4.1.1.1.

Year introduced: 1991(1975)

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Tree Number(s): D08.811.520.224.125.750

MeSH Unique ID: D011767

Registry Number: EC 4.1.1.1

Entry Terms:

• Decarboxylase, Pyruvate
• 2-Oxo Acid Carboxy-Lyase
• 2 Oxo Acid Carboxy Lyase
• Acid Carboxy-Lyase, 2-Oxo
• Carboxy-Lyase, 2-Oxo Acid
• alpha-Carboxylase
• alpha Carboxylase
• alpha-Ketoacid Carboxylase
• alpha Ketoacid Carboxylase
• Carboxylase, alpha-Ketoacid
• Pyruvic Decarboxylase
• Decarboxylase, Pyruvic

Previous Indexing:

• Carboxy-Lyases (1973-1974)
• Pyruvates (1973-1974)

All MeSH Categories
Chemicals and Drugs Category
Enzymes and Coenzymes
Enzymes
Lyases
Carbon-Carbon Lyases
Carboxy-Lyases
Pyruvate Decarboxylase