Proprotein Convertase 1
A CALCIUM-dependent endopeptidase that has specificity for cleavage at ARGININE that is near paired basic residues. It cleaves a variety of prohormones including PRO-OPIOMELANOCORTIN; PRORENIN; proenkephalins; prodynorphin; prosomatostatin; and PROINSULIN.
Year introduced: 2004
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Subheadings:
Tree Number(s): D08.811.277.656.300.760.640, D08.811.277.656.837.500, D08.811.277.656.959.350.640
MeSH Unique ID: D045664
Registry Number: EC 3.4.21.93
Entry Terms:
- Convertase 1, Proprotein
- PC3 Endoprotease
- Endoprotease, PC3
- PC3 Prohormone Convertase
- Convertase, PC3 Prohormone
- Prohormone Convertase, PC3
- Neuroendocrine Convertase PC1
- Convertase PC1, Neuroendocrine
- Prohormone Convertase 1
- Proprotein Convertase SPC3
- Convertase SPC3, Proprotein
- Proinsulin Convertase 1
- Prohormone Convertase 3
- Prohormone Convertase, PC1
- Convertase, PC1 Prohormone
- PC1 Prohormone Convertase
- PC1 Endoprotease
- Endoprotease, PC1
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