beta-Mannosidase

An enzyme that catalyzes the hydrolysis of terminal, non-reducing beta-D-mannose residues in beta-D-mannosides. The enzyme plays a role in the lysosomal degradation of the N-glycosylprotein glycans. Defects in the lysosomal form of the enzyme in humans result in a buildup of mannoside intermediate metabolites and the disease BETA-MANNOSIDOSIS.

Year introduced: 2004

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Tree Number(s): D08.811.277.450.625.750

MeSH Unique ID: D044902

Registry Number: EC 3.2.1.25

Entry Terms:

• beta Mannosidase
• beta-D-Mannosidase
• beta D Mannosidase
• beta-Mannanase
• beta Mannanase
• manA protein (beta-Mannosidase)

Previous Indexing:

• Mannosidases (1980-2003)

See Also:

• beta-Mannosidosis

All MeSH Categories
Chemicals and Drugs Category
Enzymes and Coenzymes
Enzymes
Hydrolases
Glycoside Hydrolases
Mannosidases
beta-Mannosidase