Lactase-Phlorizin Hydrolase
A multifunctional protein that contains two enzyme domains. The first domain (EC 3.2.1.62) hydrolyzes glycosyl-N-acylsphingosine to a sugar and N-acylsphingosine. The second domain (EC 3.2.1.108) hydrolyzes LACTOSE and is found in the intestinal brush border membrane. Loss of activity for this enzyme in humans results in LACTOSE INTOLERANCE.
Year introduced: 2014 (1992)
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Subheadings:
Tree Number(s): D08.811.277.450.410.100.500.500, D08.811.277.450.420.475, D08.811.641.761
MeSH Unique ID: D010694
Registry Number: EC 3.2.1.62
Entry Terms:
- Hydrolase, Lactase-Phlorizin
- Lactase Phlorizin Hydrolase
- Lactase-Glycosylceramidase
- Lactase Glycosylceramidase
- Phlorizin Hydrolase
- Hydrolase, Phlorizin
- Glycosyl Ceramidase
- Ceramidase, Glycosyl
- Glycosylceramidase
- Phloretin-Glucosidase
- Phloretin Glucosidase
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