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N-Acetylgalactosamine-4-Sulfatase

An arylsulfatase that catalyzes the hydrolysis of the 4-sulfate groups of the N-acetyl-D-galactosamine 4-sulfate units of chondroitin sulfate and dermatan sulfate. A deficiency of this enzyme is responsible for the inherited lysosomal disease, Maroteaux-Lamy syndrome (MUCOPOLYSACCHARIDOSIS VI). EC 3.1.6.12.

Year introduced: 1999

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Tree Number(s): D08.811.277.352.827.070.060, D08.811.277.352.827.180.175.060

MeSH Unique ID: D020051

Registry Number: EC 3.1.6.12

Entry Terms:

  • Arylsulfatase B
  • N-Acetylgalactosamine 4-Sulfatase
  • 4-Sulfatase, N-Acetylgalactosamine
  • N Acetylgalactosamine 4 Sulfatase
  • N-Acetylgalactosamine-4-sulfate Sulfatase
  • N Acetylgalactosamine 4 sulfate Sulfatase
  • Sulfatase, N-Acetylgalactosamine-4-sulfate
  • N-Acetylgalactosamine-4-sulphate Sulphatase
  • N Acetylgalactosamine 4 sulphate Sulphatase
  • Sulphatase, N-Acetylgalactosamine-4-sulphate
  • Arylsulfatase B1
  • B1, Arylsulfatase
  • Arylsulfatase B2
  • B2, Arylsulfatase

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