Histone Deacetylases

Deacetylases that remove N-acetyl groups from amino side chains of the amino acids of HISTONES. The enzyme family can be divided into at least three structurally-defined subclasses. Class I and class II deacetylases utilize a zinc-dependent mechanism. The sirtuin histone deacetylases belong to class III and are NAD-dependent enzymes.

Year introduced: 2003

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Tree Number(s): D08.811.277.087.520

MeSH Unique ID: D006655

Registry Number: EC 3.5.1.98

Entry Terms:

• Deacetylases, Histone
• HDAC Proteins
• Histone Deacetylase
• Deacetylase, Histone
• Histone Deacetylase Complexes
• Complexes, Histone Deacetylase
• Deacetylase Complexes, Histone
• Class I Histone Deacetylases
• Class II Histone Deacetylases

Previous Indexing:

• Acetic Acids (1971-1974)
• Amidohydrolases (1971-1974)
• Histones (1971-1974)

All MeSH Categories
Chemicals and Drugs Category
Enzymes and Coenzymes
Enzymes
Hydrolases
Amidohydrolases
Histone Deacetylases
Group III Histone Deacetylases
Sirtuins +
Histone Deacetylase 6
Mi-2 Nucleosome Remodeling and Deacetylase Complex
Histone Deacetylase 1
Histone Deacetylase 2
Retinoblastoma-Binding Protein 4
Retinoblastoma-Binding Protein 7
Sin3 Histone Deacetylase and Corepressor Complex
Histone Deacetylase 1
Histone Deacetylase 2
Retinoblastoma-Binding Protein 4
Retinoblastoma-Binding Protein 7