Cytochrome P-450 CYP11B2
A mitochondrial cytochrome P450 enzyme that catalyzes the 18-hydroxylation of steroids in the presence of molecular oxygen and NADPH-specific flavoprotein. This enzyme, encoded by CYP11B2 gene, is important in the conversion of CORTICOSTERONE to 18-hydroxycorticosterone and the subsequent conversion to ALDOSTERONE.
Year introduced: 2015 (1979)
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Subheadings:
Tree Number(s): D08.244.453.484.500, D08.244.453.915.050, D08.811.682.690.708.170.425.500, D08.811.682.690.708.170.915.050, D12.776.422.220.453.484.500, D12.776.422.220.453.915.050
MeSH Unique ID: D019405
Registry Number: EC 1.14.15.4
Entry Terms:
- Cytochrome P 450 CYP11B2
- CYP11B2
- P450c11AS
- Steroid 18-Hydroxylase
- Steroid 18 Hydroxylase
- Aldosterone Synthase
- Aldosterone Synthase Cytochrome P-450
- Aldosynthase
- Cytochrome P450Aldo
- CYP 11B2
- Cytochrome P450 11B2
- Cytochrome P-450c11AS
- Cytochrome P 450c11AS
- Corticosterone 18-monooxygenase
- 18-monooxygenase, Corticosterone
- Corticosterone 18 monooxygenase
- Corticosterone 18-hydroxylase
- 18-hydroxylase, Corticosterone
- Corticosterone 18 hydroxylase
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