Sulindac
A sulfinylindene derivative prodrug whose sulfinyl moiety is converted in vivo to an active NSAID analgesic. Specifically, the prodrug is converted by liver enzymes to a sulfide which is excreted in the bile and then reabsorbed from the intestine. This helps to maintain constant blood levels with reduced gastrointestinal side effects.
Year introduced: 1990(1979)
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Subheadings:
Tree Number(s): D02.455.426.559.847.486.875, D04.615.486.875
MeSH Unique ID: D013467
Registry Number: 184SNS8VUH
Entry Terms:
- Clinoril
- Arthrocine
- Klinoril
- Arthrobid
- MK-231
- MK231
- MK 231
- Aclin
- Apo-Sulin
- Apo Sulin
- Copal
- Kenalin
- Novo-Sundac
- Novo Sundac
- Nu-Sulindac
- Nu Sulindac
- Sulindal
- Chibret
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