Polymyxins

Basic lipopeptide antibiotic group obtained from Bacillus polymyxa. They affect the cell membrane by detergent action and may cause neuromuscular and kidney damage. At least eleven different members of the polymyxin group have been identified, each designated by a letter.

Year introduced: 1994,1963-1977

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Tree Number(s): D04.345.566.780, D10.477.750, D12.644.050.600, D12.644.066.500.600, D12.644.641.780, D12.776.543.695.054.600

MeSH Unique ID: D011113

Entry Terms:

• Polymyxin
• Polymyxin M

Pharmacologic Action:

• Anti-Bacterial Agents

All MeSH Categories
Chemicals and Drugs Category
Polycyclic Compounds
Macrocyclic Compounds
Peptides, Cyclic
Polymyxins
Colistin
Polymyxin B

All MeSH Categories
Chemicals and Drugs Category
Lipids
Lipopeptides
Polymyxins
Colistin
Polymyxin B

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Peptides
Antimicrobial Cationic Peptides
Polymyxins
Colistin
Polymyxin B

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Peptides
Antimicrobial Peptides
Antimicrobial Cationic Peptides
Polymyxins
Colistin
Polymyxin B

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Peptides
Peptides, Cyclic
Polymyxins
Colistin
Polymyxin B

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Proteins
Membrane Proteins
Pore Forming Cytotoxic Proteins
Antimicrobial Cationic Peptides
Polymyxins
Colistin
Polymyxin B