T-Lymphocytes, Cytotoxic
Immunized T-lymphocytes which can directly destroy appropriate target cells. These cytotoxic lymphocytes may be generated in vitro in mixed lymphocyte cultures (MLC), in vivo during a graft-versus-host (GVH) reaction, or after immunization with an allograft, tumor cell or virally transformed or chemically modified target cell. The lytic phenomenon is sometimes referred to as cell-mediated lympholysis (CML). These CD8-positive cells are distinct from NATURAL KILLER CELLS and NATURAL KILLER T-CELLS. There are two effector phenotypes: TC1 and TC2.
Year introduced: 1990
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Tree Number(s): A11.118.637.555.283.875, A11.118.637.555.567.550.500.200, A11.118.637.555.567.569.220.200, A11.118.637.555.567.569.500.200, A15.145.229.637.555.283.875, A15.145.229.637.555.567.550.500.200, A15.145.229.637.555.567.569.220.200, A15.145.229.637.555.567.569.500.200, A15.382.490.555.283.875, A15.382.490.555.567.550.500.200, A15.382.490.555.567.569.220.200, A15.382.490.555.567.569.500.200
MeSH Unique ID: D013602
Entry Terms:
- Cytotoxic T-Lymphocyte
- T-Lymphocyte, Cytotoxic
- T Lymphocytes, Cytotoxic
- Cytotoxic T Cells
- Cytotoxic T Cell
- T Cell, Cytotoxic
- Cytotoxic T Lymphocyte
- Cytotoxic T Lymphocytes
- Lymphocyte, Cytotoxic T
- T Lymphocyte, Cytotoxic
- Cytotoxic T-Lymphocytes
- Cell-Mediated Lympholytic Cells
- Cell, Cell-Mediated Lympholytic
- Cell-Mediated Lympholytic Cell
- Cell Mediated Lympholytic Cells
- Lympholytic Cell, Cell-Mediated
- Lympholytic Cells, Cell-Mediated
- TC1 Cells
- TC1 Cell
- Cell, TC1
- TC2 Cells
- TC2 Cell
- Cell, TC2
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