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Afatinib

A quinazoline and butenamide derivative that acts as a tyrosine kinase inhibitor of epidermal growth factor receptors (ERBB RECEPTORS) and is used in the treatment of metastatic NON-SMALL CELL LUNG CANCER.

Year introduced: 2019 (2007)

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Subheadings:

administration and dosage
adverse effects
agonists
analogs and derivatives
analysis
antagonists and inhibitors
blood
cerebrospinal fluid
chemical synthesis

chemistry
classification
economics
history
immunology
isolation and purification
metabolism
pharmacokinetics

pharmacology
poisoning
radiation effects
standards
supply and distribution
therapeutic use
toxicity
urine

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Do not include MeSH terms found below this term in the MeSH hierarchy.

Tree Number(s): D02.065.132, D03.633.100.786.188

MeSH Unique ID: D000077716

Registry Number: 41UD74L59M

Entry Terms:

(2E)-N-(4-(3-Chloro-4-fluoroanilino)-7-(((3S)-oxolan-3-yl)oxy)quinoxazolin-6-yl)-4-(dimethylamino)but-2-enamide
BIBW 2992
BIBW-2992
BIBW2992
Gilotrif
Afatinib Dimaleate
BIBW-2992-MA2
BIBW 2992 MA2
BIBW2992 MA2
BIBW-2992MA2
BIBW 2992MA2
Afatinib Maleate

Pharmacologic Action: