Quinine
An alkaloid derived from the bark of the cinchona tree. It is used as an antimalarial drug, and is the active ingredient in extracts of the cinchona that have been used for that purpose since before 1633. Quinine is also a mild antipyretic and analgesic and has been used in common cold preparations for that purpose. It was used commonly and as a bitter and flavoring agent, and is still useful for the treatment of babesiosis. Quinine is also useful in some muscular disorders, especially nocturnal leg cramps and myotonia congenita, because of its direct effects on muscle membrane and sodium channels. The mechanisms of its antimalarial effects are not well understood.
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Subheadings:
Tree Number(s): D03.132.206.719, D03.605.687.762, D03.633.100.810.762
MeSH Unique ID: D011803
Registry Number: A7V27PHC7A
Entry Terms:
- Quinine Bisulfate
- Bisulfate, Quinine
- Quinine Hydrochloride
- Hydrochloride, Quinine
- Quinine Sulfate
- Sulfate, Quinine
- Quinine Sulphate
- Sulphate, Quinine
- Quindan
- Quinimax
- Quinine Lafran
- Surquina
- Biquinate
- Myoquin
- Quinbisan
- Legatrim
- Quinbisul
- Quinsul
- Quinson
- Quinamm
- Quinine-Odan
- Quinoctal
- Strema
Pharmacologic Action: