Fusaric Acid

A picolinic acid derivative isolated from various Fusarium species. It has been proposed for a variety of therapeutic applications but is primarily used as a research tool. Its mechanisms of action are poorly understood. It probably inhibits DOPAMINE BETA-HYDROXYLASE, the enzyme that converts dopamine to norepinephrine. It may also have other actions, including the inhibition of cell proliferation and DNA synthesis.

Year introduced: 1991(1975)

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Tree Number(s): D03.066.707.200, D03.383.725.705.200

MeSH Unique ID: D005669

Registry Number: JWJ963070N

Entry Terms:

• Acid, Fusaric
• 5-Butyl-2-pyridinedicarboxylic Acid
• 5 Butyl 2 pyridinedicarboxylic Acid
• Acid, 5-Butyl-2-pyridinedicarboxylic
• Calcium Fusarate
• Fusarate, Calcium

Previous Indexing:

• Picolinic Acids (1969-1974)

Pharmacologic Action:

• Enzyme Inhibitors
• Dopamine Agents
• Nucleic Acid Synthesis Inhibitors

All MeSH Categories
Chemicals and Drugs Category
Heterocyclic Compounds
Acids, Heterocyclic
Picolinic Acids
Fusaric Acid

All MeSH Categories
Chemicals and Drugs Category
Heterocyclic Compounds
Heterocyclic Compounds, 1-Ring
Pyridines
Picolinic Acids
Fusaric Acid