Cantharidin

A toxic compound, isolated from the Spanish fly or blistering beetle (Lytta (Cantharis) vesicatoria) and other insects. It is a potent and specific inhibitor of protein phosphatases 1 (PP1) and 2A (PP2A). This compound can produce severe skin inflammation, and is extremely toxic if ingested orally.

Year introduced: 1979

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Tree Number(s): D03.633.100.127.125

MeSH Unique ID: D002193

Registry Number: IGL471WQ8P

Entry Terms:

• Cantharidine
• Cantharides

Pharmacologic Action:

• Enzyme Inhibitors
• Irritants

All MeSH Categories
Chemicals and Drugs Category
Heterocyclic Compounds
Heterocyclic Compounds, Fused-Ring
Heterocyclic Compounds, 2-Ring
Benzofurans
Cantharidin