dactolisib [Supplementary Concept]

antineoplastic agent that inhibits both phosphatidylinositol 3-kinase and mTOR

Date introduced: September 6, 2008

MeSH Unique ID: C531198

Registry Number: RUJ6Z9Y0DT

Heading Mapped to:

• Imidazoles
• Quinolines

Entry Terms:

• 2-methyl-2-(4-(3-methyl-2-oxo-8-(quinolin-3-yl)-2,3-dihydroimidazo(4,5-c)quinolin-1-yl)phenyl)propanenitrile
• 2-methyl-2-(4-(3-methyl-2-oxo-8-quinolin-3-yl-2,3-dihydro-1h-imidazo(4,5-c)quinolin-1-yl)phenyl)propanenitrile
• NVP BEZ235
• NVP-BEZ235
• NVPBEZ235
• BEZ235

Pharmacologic Action:

• Antineoplastic Agents