LIN7A lin-7 homolog A, crumbs cell polarity complex component
Gene ID: 8825, updated on 2-Nov-2024Gene type: protein coding
Also known as: LIN7; MALS1; VELI1; LIN-7A; MALS-1; TIP-33
- See all available tests in GTR for this gene
- Go to complete Gene record for LIN7A
- Go to Variation Viewer for LIN7A variants
Summary
The protein encoded by this gene is involved in generating and maintaining the asymmetric distribution of channels and receptors at the cell membrane. The encoded protein also is required for the localization of some specific channels and can be part of a protein complex that couples synaptic vesicle exocytosis to cell adhesion in the brain. [provided by RefSeq, May 2016]
Associated conditions
See all available tests in GTR for this gene
| Description | Tests |
|---|---|
| Electronic medical records and genomics (eMERGE) network exploration in cataract: Several new potential susceptibility loci. GeneReviews: Not available | |
| Genome-wide association scan of dental caries in the permanent dentition. GeneReviews: Not available |
Genomic context
- Location:
- 12q21.31
- Sequence:
- Chromosome: 12; NC_000012.12 (80792520..80937934, complement)
- Total number of exons:
- 7
Variation
| Resource | Links for this gene |
|---|---|
| ClinVar | Variants reported to ClinVar |
| dbVar | Studies and variants |
| SNP | Variation Viewer for LIN7A variants |
| Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- OMIMLink to related OMIM entry
- PubMed (OMIM)Gene links to PubMed derived from omim_pubmed_cited links
- RefSeq RNAsLink to Nucleotide RefSeq RNAs
- RefSeqGeneLink to Nucleotide RefSeqGenes
- Variation ViewerRelated Variants
IMPORTANT NOTE: NIH does not independently verify information submitted to the GTR; it relies on submitters to provide information that is accurate and not misleading. NIH makes no endorsements of tests or laboratories listed in the GTR. GTR is not a substitute for medical advice. Patients and consumers with specific questions about a genetic test should contact a health care provider or a genetics professional.