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| Status |
Public on Feb 13, 2017 |
| Title |
Expression data from colon cancer cell HCT116 mouse xenograft - Control vs. traditional Chinese medicine Astragalus membranaceus-treated conditions |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
To identify biomarkers regulated by traditional Chinese medicine Astragalus membranaceus Fischer Bge. var. mongolicus Bge. Hsiao in colorectal cancer. We have identified several differentially expressed genes including microRNAs using Affymetrix HTA-2.0 array.
In this dataset, we include the expression data obtained from colon cancer cell line HCT116 grafted into nude mice. The mice was treated either water or traditional Chinese medicine Astragalus membranaceus for 28 days. These data are used to obtain 1425 genes that are differentially expressed in response to Astragalus membranaceus treatment.
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| Overall design |
16 total samples were analyzed. The data was RMA-normalized and differentially expressed genes were selected using GeneSpring. Genes with a p < 0.05 and a fold-change > 1.5 were selected.
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| Contributor(s) |
Tseng A, Su L |
| Citation(s) |
26719057 |
| |
| Submission date |
Jul 10, 2015 |
| Last update date |
Oct 29, 2018 |
| Contact name |
Ailun Tseng |
| E-mail(s) |
heather_tseng@hotmail.com
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| Organization name |
National Central University
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| Street address |
300 Jhong Da Rd.
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| City |
Taoyuan |
| ZIP/Postal code |
32001 |
| Country |
Taiwan |
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| Platforms (1) |
| GPL17586 |
[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version] |
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| Samples (16)
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| Relations |
| BioProject |
PRJNA289513 |
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